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PhGs show significant hepatoprotective potential through their multi-target mechanisms, addressing critical processes such as oxidative stress, inflammation, apoptosis, and fibrosis

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For instance, GPX4 palmitoylation by ZDHHC20 enhances its stability, while APT2-mediated depalmitoylation promotes ferroptosis in colorectal cancer and metastasis models (61)

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The anticancer effect of water kefir was also proposed by Koh et al